Tenofovir disoproxil may be marketed under the name Viread, but generic versions are also available.Lamivudine is included in the combination tablets abacavir/lamivudine, lamivudine/zidovudine, Triumeq, Delstrigo and Dovato. Lamivudine may be marketed under the name Epivir, but generic versions are also available.It is included in the combination tablets emtricitabine/tenofovir disoproxil, Descovy, efavirenz/emtricitabine/tenofovir disoproxil, Biktarvy, Eviplera, Genvoya, Odefsey, Stribildand Symtuza. Emtricitabine is also known as Emtriva.Abacavir is included in the combination tablets abacavir/lamivudine and Triumeq. Abacavirmay be marketed under the name Ziagen, but generic versions are also available.This class of medications is sometimes referred to as the ‘backbone’ of a first-line HIV treatment combination. NRTIs disrupt the construction of a new piece of proviral DNA, thereby stopping the reverse transcription process and halting HIV replication. Nucleoside reverse transcriptase inhibitors (NRTIs), and nucleotide reverse transcriptase inhibitors (NtRTIs), often all referred to as NRTIs, work by targeting the action of an HIV protein called reverse transcriptase.Īfter the HIV virus releases its genetic material into a host cell, reverse transcriptase converts the viral RNA into DNA, a process known as ‘reverse transcription’.

Antiretroviral drug resistance testing in adult HIV-1 infection: recommendations of an International AIDS Society-USA Panel.The latest news and research on HIV treatment Hirsch MS, Brun-Vezinet F, D’Aquila RT, et al. Persistent mitochondrial dysfunction and perinatal exposure to antiretroviral nucleoside analogues. Available from URL: īlanche S, Tardieu M, Rustin P, et al. US Public Health Service Task Force recommendations for the use of antiretroviral drugs in pregnant HIV-1-infected women for maternal health and interventions to reduce perinatal HIV-1 transmission in the United States.

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